Vpx-containing dendritic cell vaccine induces CTLs and reactivates latent HIV-1 in vitro
نویسندگان
چکیده
منابع مشابه
Vpx-containing Dendritic Cell Vaccine Vectors Induce CTLs and Reactivate Latent HIV-1 in vitro
Eradication of HIV-1 from an infected individual requires a means of inducing production of virus from latently infected cells and stimulating an immune response against the infected cells. We report the development of lentiviral vectors that transduce dendritic cells (DCs) to both induce production of virus from latently infected cells and stimulate antigen-specific CTLs. The vectors package V...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2015
ISSN: 0969-7128,1476-5462
DOI: 10.1038/gt.2014.117